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Biomedical Research News from AMSNY: August 2019

Aug
20
2019

Highlights

Albert Einstein College of Medicine: Novel Therapy for Acute Migraine Shows Promise in Phase 3 Clinical Trial
A drug belonging to a new generation of acute migraine headache treatments was found to eliminate pain and reduce bothersome symptoms for people with migraine in a large-scale trial reported in the July 11 issue of The New England Journal of Medicine. Take a closer look.
SUNY Upstate Medical University: Research Shows Link Between Parkinson’s Disease and Gut Microbiome
In a paper titled “The oral microbiome of early stage Parkinson’s disease and its relationship with functional measures of motor and non motor function,” researchers from Upstate Medical University and Quadrant Biosciences Inc., a StartUp NY company based at Upstate Medical University, discovered that specific bacteria in the oral microbiome accurately differentiate early stage Parkinson’s disease (“esPD”) from healthy controls. Take a closer look.

Cancer

Columbia University Vagelos College of Physicians and Surgeons: Bacteria Engineered as Trojan Horse for Cancer Immunotherapy
The emerging field of synthetic biology-designing new biological components and systems-is revolutionizing medicine. Through the genetic programming of living cells, researchers are creating engineered systems that intelligently sense and respond to diverse environments, leading to more specific and effective solutions in comparison to current molecular-based therapeutics.  Take a closer look. 
NYU School of Medicine: Study Finds That Too Many Antioxidants May Cause Lung Cancer to Spread
A new study explains why lung cancer spreads faster in people with certain genetic changes, and suggests that taking vitamin E, long thought of as preventive, may cause the same spread. Take a closer look.
Weill Cornell Medicine: Innovative Single-Cell Genomics Technology Allows Study of Cancer Evolution in Unprecedented Detail
A new technology devised by scientists at Weill Cornell Medicine and the New York Genome Center (NYGC) enables the measurement of gene mutations and their effects on gene activity within individual cancer cells biopsied from patients. The advance, reported July 3 in Nature, allows researchers to study, in unprecedented detail, the complex dynamics of cancerous cell populations during the course of disease and in response to therapies. Take a closer look.
Renaissance School of Medicine at Stony Brook University: Engineered Cell Evolution May Provide Pathway to Halting Cancer Drug Resistance
 A significant problem when treating cancer patients remains drug resistance, which often causes chemotherapy treatments to ultimately fail. Scientists in recent years have hypothesized that cell-cell differences, also known as cell heterogeneity, aides the emergence of drug resistance. Previous studies suggest that these effects depend on drug levels. Take a closer look.

Immunology

Weill Cornell Medicine: Discovery of a New Immune Process Could Lead to Better Pain Treatments
A molecular pathway known for responding to cellular stress also produces pain-inducing molecules in immune cells, according to a new study by scientists at Weill Cornell Medicine, Dana-Farber Cancer Institute, Harvard Medical School and Wake Forest University School of Medicine. The investigators found that blocking this pathway can reduce pain. Take a closer look.
SUNY Upstate Medical University: Upstate’s Study of Vector-borne Diseases Takes Researchers to State Park
Saravanan Thangamani, PhD, professor of microbiology and immunology at Upstate Medical University and director of the SUNY Center for Environmental Health and Medicine, brought his team of researchers on a field surveillance expedition in search of ticks at Green Lakes State Park in Fayetteville. Take a closer look.
Columbia University Vagelos College of Physicians and Surgeons: Flu Fact Sheet for Parents Increases Vaccinations in Children
Young children are more likely to suffer severe, even life-threatening complications from the flu, but only around half of children in the United States get the flu vaccine. The number of children who get the flu vaccine can be increased, a new study from Columbia researchers has found, by giving parents an inexpensive and simple pamphlet about the flu in their pediatrician’s waiting room. Take a closer look.
New York Medical College: Researcher Discovers Possible Alternative to Embryonic Stem Cells as Treatment for Inflammatory Disorders
In her crusade to find reliable and ethical treatments for chronic disease, Nasreen S. Haque, Ph.D., may have discovered an alternative to embryonic stem cells (ESCs) as a treatment for inflammatory disorders. Take a closer look.

Other Studies

Icahn School of Medicine at Mount Sinai: Research Uncovers How Serotonin in the Nucleus Can Regulate Gene Expression Within Brain Cells
Serotonin, a powerful chemical that sends signals between nerve cells in the brain, has long been thought to play a key role in processes such as appetite, mood, and sleep. Now, research by neuroscientists at the Icahn School of Medicine at Mount Sinai suggests that the molecule can also enter the nucleus of these cells and help turn genes on. Take a closer look.
NYU School of Medicine: Researchers Identify Mechanism that May Drive Obesity Epidemic
A molecular trick that kept our ancient ancestors from starving may now be contributing to the obesity epidemic, a new study finds. In starvation times, researchers say, animals were more likely to survive if they could hoard and stretch out their stored energy. Even if an animal secured a rare feast, evolution smiled on the storage of excess fuel as fat, given the likelihood of a quick return to starvation. Take a closer look.

 

Renaissance School of Medicine at Stony Brook University: Can Facebook Help Predict and Monitor Disease? Study Says “Yes”
A new study reveals Facebook posts alone can predict some 21 diseases and conditions, many of them interrelated such as diabetes and hypertension, and anxiety and depression. This is one of the lead findings in a study published in PLOS ONE by researchers at Stony Brook University and Penn Medicine. The study, say the authors, has the potential with patient consent to use language in posts to not only predict disease but help monitor diseases just like physical symptoms. Take a closer look.

Grants

Albert Einstein College of Medicine: NIH Grant Funds $23 Million Study of Diseases Affecting People Living with HIV
The National Institutes of Health (NIH) has awarded a seven-year, $23 million grant to researchers at Albert Einstein College of Medicine and Montefiore Health System to study HIV and the chronic illnesses that often accompany HIV infection, including cardiovascular and lung disease, diabetes, and cancer. Take a closer look.
CUNY School of Medicine Faculty Continues to Bring In Research Funding to the University
John Martin, Medical Professor in the Department of Molecular, Cellular and Biomedical Sciences has received funding for a R01 grant from the National Institute of Neurological Disorders and Stroke.  The project, entitled “Lesion and activity dependent corticospinal tract plasticity” will be funded for five years. Take a closer look.
Albany Medical College Receives $2 Million Grant for Research on Sepsis, Other Severe Infections
Albany Medical College has been awarded a $2 million five-year grant from the National Institutes of Health’s National Institute of General Medical Sciences (NIGMS) to research the impact of severe infections on stem cell function. Take a closer look.
Touro College of Osteopathic Medicine: TouroCOM Harlem Students Win Grant
Congratulations to TouroCOM Harlem’s Nicholas Ingram, OMS-III, for winning a student educational grant from the International Association of Medical Science Educators (IAMSE)! Ingram, a co-director last year of MedAchieve –TouroCOM’s popular afterschool enrichment program for high school students — won for his proposal, “MedAchieve: Examining the Educational Outcomes of a Medical School Mentorship Program”. Take a closer look.

Faculty News

Icahn School of Medicine at Mount Sinai: Adolfo Garcia-Sastre, PhD, a Leader in the Study of Viruses, Is Elected to the National Academy of Sciences
Adolfo García-Sastre, PhD, Director of the Global Health and Emerging Pathogens Institute, and the Irene and Dr. Arthur M. Fishberg Professor of Microbiology, and Medicine (Infectious Diseases) at the Icahn School of Medicine at Mount Sinai, has been elected to the National Academy of Sciences. Take a closer look.
Albany Medical College: Dr. Megan Applewhite Named Director of Albany Medical College’s Alden March Bioethics Institute
Albany Med surgeon Megan Applewhite, M.D., has been appointed director of the Alden March Bioethics Institute (AMBI) at Albany Medical College and the John A. Balint, M.D., Chair of Medical Ethics. Dr. Applewhite, a fellowship-trained endocrine surgeon and assistant professor of surgery, has served as the interim director of AMBI for the past year. Take a closer look.

Events

New York Medical College: Conference Addresses How the Microbiome Impacts Health and Wellness
It was a full house at the Microbiome Conference at 7 Dana Road on June 12 when clinical, basic research and industry experts shared their work on microbiome science and its role in maintaining health and causing a gamut of disease. The half-day symposium featured remarks by College leadership. Take a closer look.
New York Institute of Technology College of Osteopathic Medicine Hosts Cardiovascular Researchers and Scholars at First Annual Retreat
On June 14, 150 cardiovascular and cardiology researchers, scholars, and students attended the First Annual Retreat for the NYC Area Inter-Institutional Cardiovascular Seminar Series at NYIT de Seversky Mansion. Take a closer look.

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