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Role of osteocalcin outside of bone

Institution:

Columbia University College Of Physicians and Surgeons

Researchers:

Gerard Karsenty, MD, PhD, the Paul A. Marks Professor of Genetics and Development, Professor of Medicine, and Chair of the Department of Genetics and Development at Columbia University College of Physicians & Surgeons

Impact:

Karsenty’s research has uncovered that osteocalcin, a hormone that is released by bone, plays several important roles in human health. In a series of studies in mice, he found that osteocalcin helps to regulate blood sugar by stimulating the release of insulin into the bloodstream and improving the uptake of glucose in cells throughout the body. Karsenty also found that osteocalcin helps to regulate male fertility, brain development, and cognitive functions such as learning and memory.

Timeline:

2007-2013

Topics

AgingBasic ScienceCancerCardiovascularClinical ResearchDiagnosticsDrug DevelopmentFeaturedGeneticsImmune SystemInfectious DiseaseMedical DeviceMental HealthNeurodegenerativeNobel PrizePediatricsPublic HealthRespiratorySurgical AdvancementTechnologyTreatment AdvancesVaccines

Schools

Albany Medical CollegeAlbert Einstein College of MedicineCity University of New York School of MedicineColumbia University College Of Physicians and SurgeonsHofstra Northwell School of Medicine at Hofstra UniversityIcahn School of Medicine at Mount SinaiJacobs School of Medicine and Biomedical Sciences, the University at BuffaloNew York Institute of Technology College of Osteopathic MedicineNew York Medical CollegeNew York University School of MedicineSchool of Medicine and Dentistry at the University of Rochester Medical CenterStony Brook University School of MedicineSUNY Downstate Medical CenterSUNY Upstate Medical UniversityTouro College of Osteopathic MedicineWeill Cornell MedicineWeill Cornell Medicine, NewYork-Presbyterian