Institution:Columbia University College Of Physicians and Surgeons
Richard Mayeux, MD, Gertrude H. Sergievsky Professor of Neurology, Psychiatry, and Epidemiology, Chair of the Department of Neurology, and co-director of the Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University College of Physicians & Surgeons
Mayeux led an international team of researchers that discovered a second gene (after ApoE4) implicated in late-onset Alzheimer’s disease. Certain variants of the gene, they discovered, interfere with normal function of SORL1, leading to increased production of toxic amyloid beta protein in the brain. His Alzheimer’s disease research earned him the Potamkin Award from the American Academy of Neurology (2007), the John M. Sterns Lifetime Achievement Award in Medicine from the New York Academy of Medicine (2008), and
a Henry Wisniewski Lifetime Achievement Award in Alzheimer’s Disease Research (2009).