Creation of a prototype vaccine against tuberculosis that works better in animal models than the current TB vaccine


Albert Einstein College of Medicine


William Jacobs, Jr., PhD, professor of microbiology & immunology and genetics at Albert Einstein College of Medicine, and Howard Hughes Medical Institute investigator


Tuberculosis (TB) is caused by a bacterium called Mycobacterium tuberculosis. The bacteria usually attack the lungs, but TB bacteria can attack any part of the body such as the kidney, spine and brain. If not treated properly, TB disease can be fatal. The prototype vaccine stems from genetic manipulation of the bacterium.