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Biomedical Research Newsletter from AMSNY: March 2018

Mar
29
2018

Highlights

Weill Cornell Medicine: Tri-Institutional Therapeutics Discovery Institute Drug Candidates “Graduate” to Next Phase of Development
 
When the Tri-Institutional Therapeutics Discovery Institute launched just over four years ago, nothing like it existed in academia. The nonprofit academic corporation – a joint venture between Memorial Sloan Kettering Cancer Center, The Rockefeller University and Weill Cornell Medicine, with Takeda Pharmaceutical Company Ltd. as their partner – was tasked with expediting the development of innovative new drugs and, more recently, antibodies, based on early discoveries at the three institutions. Take a closer look.
Columbia University College of Physicians and Surgeons: Kids from Low-Income Areas Fare Worse After Heart Surgery, Finds Study

Children from low-income neighborhoods had a higher mortality rate and higher hospital costs after heart surgery compared with those from higher-income neighborhoods, found a national study of more than 86,000 kids with congenital heart disease. The magnitude of the neighborhood effect, which persisted even after accounting for race, type of insurance, and hospital, was similar for children of all disease severities. Take a closer look.

Cancer

Columbia University College of Physicians and Surgeons: Precision Oncology – New Tests Look Beyond Genes
Two new precision medicine tests that look beyond cancer genes to identify novel therapeutic targets have just received New York State Department of Health approval and are now available to both oncologists and cancer researchers for use at the front lines of patient care. Take a closer look.
Weill Cornell Medicine Scientists Discover New Nanoparticle, Dubbed Exomeres

A new cellular messenger discovered by Weill Cornell Medicine scientists may help reveal how cancer cells co-opt the body’s intercellular delivery service to spread to new locations in the body. Take a closer look.

Neurology

New York Medical College Researcher Sheds New Light on Root Cause of CTE
As an expert in his field, Patric K. Stanton, Ph.D., professor of cell biology and anatomy and of neurology, and a team at New York Medical College were called upon to join an elite contingent of researchers studying the origins of Chronic Traumatic Encephalopathy (CTE).  Take a closer look.
Touro College of Osteopathic Medicine: A New Way to Treat Strokes

A TouroCOM Harlem student presented a groundbreaking new approach to treating strokes at this year’s International Stroke Conference. Take a closer look.

Icahn School of Medicine at Mount Sinai: Study Draws Links Between Physical Characteristics, Like Age and Body Mass Index, and Brain Health in Psychosis Patients
Mount Sinai researchers have shown, for the first time, the complex web of links between physical and behavioral characteristics, like age, body mass index (BMI), and substance use, and specific patterns of brain structure and function in patients with psychosis. The study is important because many of these characteristics can be targeted clinically to improve brain health in these patients. Take a closer look.
NYU School of Medicine: Therapeutic Antibodies Protected Nerve-Muscle Connections in a Mouse Model of Lou Gehrig’s Disease
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, causes lethal respiratory paralysis within several years of diagnosis. There are no effective treatments to slow or halt this devastating disease. Take a closer look.
Icahn School of Medicine at Mount Sinai: Risk of Cognitive Decline Reduced for People 85 and Older With High Cholesterol, Mount Sinai Researchers Find
People aged 85 and older whose total cholesterol had increased from their levels at midlife had a reduced risk for marked cognitive decline, compared with those a decade younger whose cholesterol was similarly elevated, Mount Sinai researchers report in a new study. Take a closer look.

Other Studies

Zucker School of Medicine at Hofstra/Northwell: Researchers Discover E. Coli Hormone Reduces Inflammation

Donald and Barbara Zucker School of Medicine at Hofstra/Northwell professor of medicine, Jesse Roth, MD, FACP, and fellow investigators at the Feinstein Institute for Medical Research recently discovered that the E. coli bacteria found in our intestines are communicating with cells throughout our bodies to reduce inflammation. Take a closer look. 

NYU School of Medicine: Study Validates Software Tool to Assess Mortality Risk in Older Patients With Orthopedic Fractures
Analytic software developed by orthopedic trauma surgeons at NYU Langone Health accurately identifies which middle-aged and elderly patients face a greater mortality risk following surgery for an orthopedic fracture, according to a new study. Take a closer look.
SUNY Upstate Medical University is Part of Multi-Institution Study Examining the Rise in Mining-Related Lung Disease
Researchers at Upstate Medical University are part of $1.8 million study involving nine institutions that will investigate the recent increase in severe lung disease among coal mine workers with a close examination of the link between mine dust exposures and severe lung disease in miners. Take a closer look.
Zucker School of Medicine at Hofstra/Northwell: New Research Reveals the Role of Cells in Rheumatoid Arthritis and Lupus

Feinstein Institute for Medical Research professors Betty Diamond, MD, and Peter K. Gregersen, MD,release data from their National Institutes of Health (NIH) research which reveals our cells’ roles in rheumatoid arthritis and lupus. Take a closer look.

New York Medical College and Touro Launch Shark Tank-Inspired Forum to Invest in Israeli Biotechnology
In a unique forum loosely based on the hit television show, Shark Tank, executives from three Israeli biotech companies pitched their medical products to an exclusive group of entrepreneurs interested in helping the companies develop and market their products in the U.S. Take a closer look.
Read more from the medical schools!

Albany Medical College
Albert Einstein College of Medicine
CUNY School of Medicine
Columbia University College of Physicians and Surgeons
Icahn School of Medicine at Mount Sinai
Jacobs School of Medicine & Biomedical Sciences at University at Buffalo
New York Institute of Technology College of Osteopathic Medicine
New York Medical College
NYU School of Medicine
Stony Brook Medicine
SUNY Downstate Medical Center
SUNY Upstate Medical University
Touro College of Osteopathic Medicine
University of Rochester School of Medicine & Dentistry
Weill Cornell Medicine
Zucker School of Medicine at Hofstra Northwell

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