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Newsletter > Biomedical Research News from AMSNY: February 2024

02/27/2024

Biomedical Research News from AMSNY: February 2024

Highlights

Jacobs School of Medicine & Biomedical Sciences at University at Buffalo: Health Disparities at the Beginning Stages of Life is Focus of NIH-funded Study at UB

A University at Buffalo researcher has received a five-year, $3.4 million grant to begin a study that will examine how parents’ mental health and socio-economic factors impact health disparities at the very beginning stages of life. Learn more.

New York Medical College: Socioeconomic Disparities Exist in Treatment of Teen Femoral Fractures

Children and adolescents from poor socioeconomic backgrounds are more likely to experience delayed treatment for femoral fractures leading to worse outcomes and increased healthcare costs according to a new study by NYMC faculty and student researchers recently published in Injury. Learn more.

COVID-19

Weill Cornell Medicine: SARS-CoV-2 Can Infect Dopamine Neurons Causing Senescence

A new study reported that SARS-CoV-2, the virus that causes COVID, can infect dopamine neurons in the brain and trigger senescence—when a cell loses the ability to grow and divide. The researchers from Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and Columbia University Vagelos College of Physicians and Surgeons suggest that further research on this finding may shed light on the neurological symptoms associated with long COVID such as brain fog, lethargy and depression. Learn more.

Cancer

Columbia University Vagelos College of Physicians and Surgeons: When it Comes to Alcohol, Less is More

Drinking alcohol — even in moderation — can take a serious toll on the body. According to the National Cancer Institute, there is a strong scientific consensus that drinking alcohol increases the risk for several types of cancer, including head and neck cancer, liver cancer, esophageal cancer, breast cancer, and colorectal cancer. But until recently, the question still remained whether reducing alcohol intake or stopping drinking altogether reduces the risk of cancer. Learn more.

Cardiology

NYU Grossman School of Medicine: Supportive, Stable Caregiving in Childhood Protects Heart Health in Adulthood

Previous research has established that childhood experience with abuse, neglect, and substance use in the home can worsen a person’s heart health throughout their life. New research, however, shows that receiving consistent warmth from a caregiver during childhood protects cardiovascular health later in life, according to a study led by NYU Grossman School of Medicine and The Ohio State University Wexner Medical Center. Learn more.

New York Medical College: New Study Urges Changes to Hemorrhagic Stroke Standards to Save Lives

Although Intracerebral hemorrhage (ICH) accounts for only 15 to 20 percent of all strokes, it is by far the deadliest and most disabling form of stroke, with a mortality rate of approximately 30 percent.  While a highly standardized and optimized workflow has been adopted worldwide for treating acute ischemic stroke no such time-based emergency protocols are in widespread use for ICH. Stephan Mayer, M.D., professor of neurology and neurosurgery at New York Medical College, along with an international consortium of doctors, is now urging this to change, in a study published in Stroke. Learn more.

Neurology

NYU Grossman School of Medicine: Brain Mechanism Teaches Mice to Avoid Bullies

Like humans, mice live in complex social groups, fight over territory and mates, and learn when it is safer to avoid certain opponents. After losing even a brief fight, the defeated animals will flee from the mice that hurt them for weeks afterward, a new study shows. Learn more.

Albert Einstein College of Medicine: Fire in the Brain

Inflammation is a condition in which tissues become reddened, swollen, hot, and often painful. It’s what happens when the immune system defends the body against some sort of threat—when you develop a viral or bacterial infection, for example, or burn your hand. In fact, the immune system’s arsenal includes pro-inflammatory signaling proteins such as cytokines, which encourage tissue inflammation as a way to trap and kill microbes and encourage the healing process. Learn more.

Jacobs School of Medicine & Biomedical Sciences at University at Buffalo: Research into the Nature of Memory Reveals How Cells That Store Information are Stabilized Over Time

Think of a time when you had two different but similar experiences in a short period. Maybe you attended two holiday parties in the same week or gave two presentations at work. Shortly afterward, you may find yourself confusing the two, but as time goes on that confusion recedes and you are better able to differentiate between these different experiences. Learn more.

More Studies

SUNY Downstate Health Sciences University: Revolutionizing Kidney Treatment

Moro O. Salifu, M.D., MPH, MBA, MACP, a renowned figure in medical innovation, holds prestigious positions as Chairman of Medicine, Chief of Nephrology, and Director of Interventional Nephrology. He has earned national and global recognition for his revolutionary discovery and role of the human platelet F11 receptor, which has significantly advanced our understanding of stenosis in the vascular system. Learn more.

University of Rochester School of Medicine & Dentistry: Calcium Channel Blockers Key to Reversing Myotonic Dystrophy Muscle Weakness, Study Finds

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these symptoms in animal models of the disease. The researchers believe this class of drugs, widely used to treat a number of cardiovascular diseases, hold promise as a future treatment for DM1. Learn more.

Columbia University Vagelos College of Physicians and Surgeons:Gone Fishing: Zebrafish Studies May Lead to New Treatments for Osteoarthritis

Cut a finger and the wound scabs over and heals itself. Break a leg and new bone fills in the gap. So why are joints debilitated by osteoarthritis so bad at repairing themselves? A tiny, striped, freshwater fish native to South Asia—the zebrafish—may hold the answer. Learn more.

Weill Cornell Medicine: Structural Study Points the Way to Better Malaria Drugs

Structural insights into a potent antimalarial drug candidate’s interaction with the malaria parasite Plasmodium falciparum have paved the way for drug-resistant malaria therapies, according to a new study by researchers at Weill Cornell Medicine and Van Andel Institute. The antimalarial molecule, TDI-8304, is one of a new class of experimental therapeutics that targets the proteasome, an essential, multiprotein complex in P. falciparum cells. Learn more.

Awards & Grants

University of Rochester School of Medicine & Dentistry: New NIH-funded Center Could Soon Reduce the Need for Pharmaceutical Trials on Animals 

The University of Rochester will house a new national center focused on using tissue-on-chip technology to develop drugs more rapidly and reduce the need for animal trials. The National Institutes of Health awarded a $7.5 million grant to establish the Translational Center for Barrier Microphysiological Systems (TraCe-bMPS) at Rochester in partnership with Duke University. Learn more.

Icahn School of Medicine at Mount Sinai Receives Helmsley Charitable Trust Grant for Crohn’s Disease Research

The Icahn School of Medicine at Mount Sinai has been awarded a grant of more than $4 million from The Leona M. and Harry B. Helmsley Charitable Trust to support an innovative research project aimed at understanding the early stages of Crohn’s disease before noticeable symptoms develop. Learn more.

Albany Medical College: $3.9M NIH Grant Awarded for Research on Long Covid

Scientists at Albany Medical College have been awarded a five-year, $3.9 million grant from the National Institutes of Health (NIH) to study biomarkers present in the blood of patients who have had Covid-19 but continue to experience symptoms for weeks or months after the initial infection. Learn more.

Renaissance School of Medicine at Stony Brook University: Neuroscientist Receives $2.2 Million for Pivotal PTSD Research

Prerana Shrestha, PhD, Assistant Professor in the Department of Neurobiology and Behavior in the Renaissance School of Medicine at Stony Brook University, has received a $2.2 million grant from the National Institute of Mental Health (NIMH) for research on why individuals with Post-Traumatic Stress Disorder (PTSD) have persistent intrusive memories of the traumatic experience. Learn more.

Albany Medical College and UAlbany Scientists Team Up to Study Neurodegenerative Diseases With Support From $2.9M NIH Grant

Scientists at Albany Medical College and UAlbany’s RNA Institute have been awarded a grant totaling more than $2.9 million from the National Institutes of Health (NIH) to study and develop new drugs to treat spinocerebellar ataxias (SCAs), a group of rare neurological disorders caused by mutations in specific genes that affect functions such as balance and coordination. Learn more.

Albert Einstein College of Medicine Faculty Receive NIH Career Development Awards

The National Institutes of Health (NIH) offers career development grants to advance the careers of young researchers. Senior postdoctoral fellows or early-career faculty members who receive these grants, referred to as K awards, have the opportunity to conduct independent research and eventually compete for major grant support. Other K awards are given to mid-career or senior investigators for their research and to mentor junior faculty. Learn more.

Icahn School of Medicine at Mount Sinai: Two Leading Mount Sinai Brain Scientists Recognized for Outstanding Contributions to Neuropsychopharmacology

Helen S. Mayberg, MD, Founding Director of the Nash Family Center for Advanced Circuit Therapeutics at Mount Sinai, and James Murrough, MD, PhD, Director of the Depression and Anxiety Center for Discovery and Treatment at Mount Sinai, were selected to receive 2023 Honorific Awards from the American College of Neuropsychopharmacology (ACNP) for their outstanding contributions to the field. Neuropsychopharmacology is the study of the neural mechanisms by which drugs affect behavior. Learn more.

More News

Renaissance School of Medicine at Stony Brook University: Stony Brook Heart Institute Among First in Nation to Perform Leading-Edge Blood Pressure Treatment

The Stony Brook Heart Institute at Stony Brook University Hospital is expanding its advanced treatment options for those with high blood pressure. The Heart Institute is among the first in the nation to perform ultrasound renal denervation — a groundbreaking, minimally invasive technique to treat high blood pressure for those with resistant hypertension. Learn more.

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