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Xiaflex, a non-surgical treatment for the chronic hand condition Dupuytren’s contracture

Institution:

Stony Brook University School of Medicine

Researchers:

Lawrence Hurst, MD, and Marie Badalamente, PhD, in the Department of Orthopaedics at Stony Brook Medicine

Impact:

Dupuytren’s contracture is a disorder in which excess collagen accumulation in the palm and fingers causes thick, inflexible cords to form, triggering a progressive and permanent curling up of the fingers. Historically, the standard of care has been surgery to cut the cords. But thanks to the investigational research by Drs. Badalamente and Hurst, Xiaflex, a non-surgical treatment received FDA approval.

Timeline:

Research began in the mid-1990s; approved by the FDA in 2010

Topics

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Schools

Albany Medical CollegeAlbert Einstein College of MedicineCity University of New York School of MedicineColumbia University College Of Physicians and SurgeonsHofstra Northwell School of Medicine at Hofstra UniversityIcahn School of Medicine at Mount SinaiJacobs School of Medicine and Biomedical Sciences, the University at BuffaloNew York Institute of Technology College of Osteopathic MedicineNew York Medical CollegeNew York University School of MedicineSchool of Medicine and Dentistry at the University of Rochester Medical CenterStony Brook University School of MedicineSUNY Downstate Medical CenterSUNY Upstate Medical UniversityTouro College of Osteopathic MedicineWeill Cornell MedicineWeill Cornell Medicine, NewYork-Presbyterian